RAGE Polyclonal Antibody, 20ul[BT-AP07639] Gel & Buffers This gene is one of

This gene is one of a cluster of highly related genes located at chromosomal region 19q13

This protein contains a core domain in the N-terminus

while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer

The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine

15-kD protein

RAGE Polyclonal Antibody, 20ul[BT-AP07639] Gel & Buffers This gene is one ofThe advanced glycosylation end product (AGE) receptor encoded by AGER is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non protein coding