NIPBL Polyclonal Antibody, 20ul DNA Fragments Mutations in this gene cause

Mutations in this gene cause Charcot-Marie-Tooth disease| type 2A1

tissue specificity:Most abundant expression in the heart and pancreas

The protein localizes to the outer membrane of mitochondria

MSC is a downstream target of the B-cell receptor signal transduction pathway

an LDL receptor-like domain

NIPBL Polyclonal Antibody, 20ul DNA Fragments Mutations in this gene causeThis gene encodes the homolog of the Drosophila melanogaster Nipped B gene product and fungal Scc2 type sister chromatid cohesion proteins. The Drosophila protein facilitates enhancer promoter communication of remote enhancers and plays a role in developmental regulation. It is also homologous to a family of chromosomal adherins with broad roles in sister chromatid cohesion, chromosome condensation, and DNA repair. The human protein has a bipartite