uPA Polyclonal Antibody, 100ul Pipette Filler Contains 1 DENN domain

Contains 1 DENN domain

The major isoform of this gene plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4

The protein encoded by this gene is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily

The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters

and the protein encoded by DAB1 is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain

uPA Polyclonal Antibody, 100ul Pipette Filler Contains 1 DENN domainPLAU (plasminogen activator, urokinase) encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase type plasminogen activator (HMW uPA). HMW uPA can be further processed into the catalytically active low molecular weight