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Cripto Monoclonal Antibody, 100ul DNA Libraries Synthesis which regulates trafficking in both

SKU: 46307822484

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Cripto Monoclonal Antibody, 100ul DNA Libraries Synthesis which regulates trafficking in bothThis gene encodes an epidermal growth factor related protein that contains a cripto, FRL 1, and cryptic domain. The encoded protein is an extracellular, membrane bound signaling protein that plays an essential role in embryonic development and tumor growth. Mutations in this gene are associated with forebrain defects. Pseudogenes of this gene are found on chromosomes 2, 3, 6, 8, 19 and X. Alternate splicing results in multiple transcript variants.

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Description

which regulates trafficking in both a retrograde (from early endosomes and Golgi to the endoplasmic reticulum) and an anterograde (from the Golgi to the plasma membrane) directions

a member of the histidine triad gene family

Sulfatases hydrolyze sulfate esters from sulfated steroids

Binding of the encoded ligand to NKG2D leads to activation of several signal transduction pathways

This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14

Cripto Monoclonal Antibody, 100ul DNA Libraries Synthesis which regulates trafficking in bothThis gene encodes an epidermal growth factor related protein that contains a cripto, FRL 1, and cryptic domain. The encoded protein is an extracellular, membrane bound signaling protein that plays an essential role in embryonic development and tumor growth. Mutations in this gene are associated with forebrain defects. Pseudogenes of this gene are found on chromosomes 2, 3, 6, 8, 19 and X. Alternate splicing results in multiple transcript variants.

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