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Flt3 Polyclonal Antibody, 100ul[BT-AP09206] Gene Editing An important paralog of this

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Flt3 Polyclonal Antibody, 100ul[BT-AP09206] Gene Editing An important paralog of thisThis gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis,

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Description

An important paralog of this gene is OLFM1

|subunit:Heterotetramer that consists of two anti-parallel arranged heterodimers| each one formed by a p18 subunit and a p12 subunit

TORC1 binds to and is inhibited by FKBP12-rapamycin

Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease

tissue specificity:Isoform 1 is highly expressed in adult and fetal heart

Flt3 Polyclonal Antibody, 100ul[BT-AP09206] Gene Editing An important paralog of thisThis gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis,

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