Apaf-1-ALT Polyclonal Antibody, 50ul Peripheral Blood Separation Tube POM121 (POM121 transmembrane nucleoporin) encodes

POM121 (POM121 transmembrane nucleoporin) encodes a transmembrane protein that localizes to the inner nuclear membrane and forms a core component of the nuclear pore complex

Aberrant splice variants expressed in tumor cell lines have also been described

Endophilin B1 is a member of the B subgroup of the Endophilin family that is required for maintenance of mitochondrial morphology and for the regulation of the outer mitochondrial membrane dynamics

a novel family that is similar to the chemokine and the transmembrane 4 superfamilies of signaling molecules

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Apaf-1-ALT Polyclonal Antibody, 50ul Peripheral Blood Separation Tube POM121 (POM121 transmembrane nucleoporin) encodesAPAF1 encodes a cytoplasmic protein that initiates apoptosis. This protein (apoptotic peptidase activating factor 1) contains several copies of the WD 40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent