GCSc-Gamma Polyclonal Antibody, 20ul Reservoirs and dihydroorotase
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GCSc-Gamma Polyclonal Antibody, 20ul Reservoirs and dihydroorotaseGlutamate cysteine ligase, also known as gamma glutamylcysteine synthetase is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. GCLC encodes Glutamate cysteine ligase catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22 p21. Mutations at GCLC have been associated with hemolytic anemia due to
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