ITGA3 Rabbit Polyclonal Antibody, 50ul Miscellaneous It has been implicated in

It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates

This protein is a major component of the calyx in the perinuclear theca of mammalian sperm heads

Mutations in this gene may be associated with Poretti-Boltshauser syndrome

The epitopes that elicit these autoantibodies are localized largely to the non-collagenous C-terminal domain of the protein

The protein encoded by this gene is a regulatory component of PI3K

ITGA3 Rabbit Polyclonal Antibody, 50ul Miscellaneous It has been implicated inThe gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function as cell surface adhesion molecules. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 3 subunit. This subunit joins with a beta 1 subunit to form an integrin that interacts with extracellular matrix