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Rat Vascular Endothelial Cell Growth Factor D, VEGF-D ELISA Kit, 96T Enzymes Fibroblast growth factor receptor 1

SKU: 48262777815

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Rat Vascular Endothelial Cell Growth Factor D, VEGF-D ELISA Kit, 96T Enzymes Fibroblast growth factor receptor 1Growth factor active in angiogenesis, lymphangiogenesis and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in the formation of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR 3 (Flt4) receptor (By similarity).

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Description

Fibroblast growth factor receptor 1 encoded by FGFR1 is a member of the fibroblast growth factor receptor (FGFR) family

In cooperation with NOD2 involved in an inflammasome activated by bacterial muramyl dipeptide leading to caspase-1 activation

Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6 (PubMed: 22000856)

PubMed: 26280335

and it is required for the association of centromere-associated protein E with the kinetochore

Rat Vascular Endothelial Cell Growth Factor D, VEGF-D ELISA Kit, 96T Enzymes Fibroblast growth factor receptor 1Growth factor active in angiogenesis, lymphangiogenesis and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in the formation of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR 3 (Flt4) receptor (By similarity).

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