Phospho-Bcl-2 (T69) Polyclonal Antibody, 100ul DNA/RNA Isolation & Purification Expression of this gene is

Expression of this gene is associated with a poor prognosis for glioma patients

which shift from the inactive to the active state through the action of RALGDS (MIM 601619)

It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation

The encoded cytosolic protein and mitochondrial glycerol-3-phosphate dehydrogenase also form a glycerol phosphate shuttle that facilitates the transfer of reducing equivalents from the cytosol to mitochondria

A similar but distinct gene (TAF9L) has been found on the X chromosome and a pseudogene has been identified on chromosome 19

Phospho-Bcl-2 (T69) Polyclonal Antibody, 100ul DNA/RNA Isolation & Purification Expression of this gene isBCL2 (BCL2, apoptosis regulator) encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.