Trk A Polyclonal Antibody, 50ul[BT-AP09212] Endonucleases & Exonucleases Three alternatively spliced transcript variants

Three alternatively spliced transcript variants that encode different protein isoforms have been described for RBBP5

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CD2BP2 encodes a bi-functional protein (CD2 cytoplasmic tail binding protein 2)

the protein mutated in Huntington disease (HD)

Related pseudogenes have been identified on chromosomes 5

Trk A Polyclonal Antibody, 50ul[BT-AP09212] Endonucleases & Exonucleases Three alternatively spliced transcript variantsNTRK1 encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self mutilating behavior,