IRF-3 Polyclonal Antibody, 20ul[BT-AP04628] Human Genome Knockout Libraries The protein encoded by BAIAP2L2

The protein encoded by BAIAP2L2 (BAI1 associated protein 2 like 2) binds phosphoinositides and promotes the formation of planar or curved membrane structures

6-linked sialic acid

and it may have a physiological role in regulating ADP-ribosylation factor protein 6 (ARF) functions

ADCY7 encodes a membrane-bound adenylate cyclase that catalyses the formation of cyclic AMP from ATP and is inhibitable by calcium

The BARD1/BRCA1 interaction is disrupted by tumorigenic amino acid substitutions in BRCA1

IRF-3 Polyclonal Antibody, 20ul[BT-AP04628] Human Genome Knockout Libraries The protein encoded by BAIAP2L2IRF3 encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed