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A20 Polyclonal Antibody, 50ul[BT-AP00064] Site-directed Mutagenesis which together with CD3-epsilon

SKU: 49572680560

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A20 Polyclonal Antibody, 50ul[BT-AP00064] Site-directed Mutagenesis which together with CD3-epsilonTNFAIP3 was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). TNF alpha induced protein 3 encoded by TNFAIP3 is a zinc finger protein and ubiqitin editing enzyme, and has been shown to inhibit NF kappa B activation as well as TNF mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine mediated immune and inflammatory responses.

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Description

which together with CD3-epsilon

Alternative splicing in the 5' untranslated region results in multiple transcript variants that encode the same protein

B-cell linker bridges B cell receptor-associated kinase activation with downstream signaling pathways

The transcript for this particular family member uses more than one polyadenylation site

as described in human patients with lissencephaly

A20 Polyclonal Antibody, 50ul[BT-AP00064] Site-directed Mutagenesis which together with CD3-epsilonTNFAIP3 was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). TNF alpha induced protein 3 encoded by TNFAIP3 is a zinc finger protein and ubiqitin editing enzyme, and has been shown to inhibit NF kappa B activation as well as TNF mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine mediated immune and inflammatory responses.

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