Phospho-B23 (T234) Polyclonal Antibody, 100ul Deep Well Plates elegans counterpart of this gene

elegans counterpart of this gene is found to regulate synaptic vesicle transport possibly by integrating JNK signaling and kinesin-1 transport

It is one of seven related genes or pseudogenes found in a cluster| thought to result from gene duplication| on chromosome 22

The encoded protein may be a regulator of Wnt signaling

Mutations in a related gene on chromosome X cause X-linked amelogenesis imperfecta

both of which serve as precursors in the production of signaling molecules

Phospho-B23 (T234) Polyclonal Antibody, 100ul Deep Well Plates elegans counterpart of this geneNPM1 encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of NPM1 have been identified.