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S12A1 Rabbit Polyclonal Antibody, 20ul Pathway and Network Analysis This gene encodes a nuclear

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SEK85.00 SEK115.00

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S12A1 Rabbit Polyclonal Antibody, 20ul Pathway and Network Analysis This gene encodes a nuclearThis gene encodes a kidney specific sodium potassium chloride cotransporter that is expressed on the luminal membrane of renal epithelial cells of the thick ascending limb of Henle's loop and the macula densa. It plays a key role in concentrating urine and accounts for most of the NaCl resorption. It is sensitive to such diuretics as furosemide and bumetanide. Some Bartter like syndromes result from defects in this gene. Alternative splicing results

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Description

This gene encodes a nuclear protein containing a SWIRM domain

It was identified as a gene induced during terminal differentiation in melanoma cells

Serine/threonine-protein kinase mTOR acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex

(PMID: 20173098 ) From BLAST result

Huntington's disease (HD)

S12A1 Rabbit Polyclonal Antibody, 20ul Pathway and Network Analysis This gene encodes a nuclearThis gene encodes a kidney specific sodium potassium chloride cotransporter that is expressed on the luminal membrane of renal epithelial cells of the thick ascending limb of Henle's loop and the macula densa. It plays a key role in concentrating urine and accounts for most of the NaCl resorption. It is sensitive to such diuretics as furosemide and bumetanide. Some Bartter like syndromes result from defects in this gene. Alternative splicing results

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