FEN-1 Polyclonal Antibody, 100ul Monoclonal Antibody Preparation The encoded protein is the

The encoded protein is the largest subunit of the activating signal cointegrator 1 complex that is involved in DNA repair and resistance to alkylation damage

This protein cleaves and activates caspases 3 and 7

This encoded protein may play a role in protein kinase C signaling

RFX2 (regulatory factor X2) is a member of the regulatory factor X gene family

It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP)

FEN-1 Polyclonal Antibody, 100ul Monoclonal Antibody Preparation The encoded protein is theFlap endonuclease 1 encoded by FEN1 removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis. Direct physical interaction between this protein and AP endonuclease 1 during long patch base excision repair provides coordinated loading of the proteins onto the substrate, thus passing the substrate from one enzyme to another. The protein is a member of the XPG RAD2 endonuclease family and is