PCNA Polyclonal Antibody, 20ul[BT-AP12847] NGS Oligos Contains 2 chromo domains

Contains 2 chromo domains

Each first exon encodes the substrate binding site| and is regulated by its own promoter

May recognize and hydrolyze the peptide bond at the C-terminal Gly of ubiquitin

This gene encodes a protein that contains multiple transmembrane regions and two pore-forming P domains and functions as a pH-dependent potassium channel

which is abundant in the eukaryotic cytosol and may be involved in the transport and assembly of newly synthesized proteins

PCNA Polyclonal Antibody, 20ul[BT-AP12847] NGS Oligos Contains 2 chromo domainsThe protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6 dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have