Human Rho Gtpase-activating Protein 22, ARHGAP22 ELISA Kit , 96T sgRNA Library Construction The two interacting proteins are

The two interacting proteins are thought to act as a transcriptional repressor for promoters which are activated by the E2F1 transcription factor

A subtype of IgA pemphigus| a life-threatening autoimmune disease| is characterized by the presence of autoantibodies that target the encoded protein

MyD88-mediated signaling in intestinal epithelial cells is crucial for maintenance of gut homeostasis and controls the expression of the antimicrobial lectin REG3G in the small intestine (By similarity)

This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins

Belongs to the G-protein coupled receptor 2 family

Human Rho Gtpase-activating Protein 22, ARHGAP22 ELISA Kit , 96T sgRNA Library Construction The two interacting proteins areRho GTPase activating protein involved in the signal transduction pathway that regulates endothelial cell capillary tube formation during angiogenesis. Acts as a GTPase activator for the RAC1 by converting it to an inactive GDP bound state. Inhibits RAC1 dependent lamellipodia formation. May also play a role in transcription regulation via its interaction with VEZF1, by regulating activity of the endothelin 1 (EDN1) promoter (By similarity).