Nrl Polyclonal Antibody, 20ul Plasma MARCH4 reduces surface accumulation of

MARCH4 reduces surface accumulation of several membrane glycoproteins by directing them to the endosomal compartment

Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane

alpha and beta

featuring a high capacity of 50 kDa

A similar protein in mouse is required for early development of the embryo

Nrl Polyclonal Antibody, 20ul Plasma MARCH4 reduces surface accumulation ofNRL encodes a basic motif leucine zipper transcription factor of the Maf subfamily. Neural retina leucine zipper is conserved among vertebrates and is a critical intrinsic regulator of photoceptor development and function. Mutations in NRL have been associated with retinitis pigmentosa and retinal degenerative diseases.