p107 Polyclonal Antibody, 50ul RNA Synthesis Overexpression of CCNE1 has been

Overexpression of CCNE1 has been observed in many tumors

The protein encoded by this gene belongs to the SMAD| a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C

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elegans unc119 protein and it can functionally complement the C

Depletion of this protein in cancer cells dramatically inhibited cell proliferation and induced apoptosis

p107 Polyclonal Antibody, 50ul RNA Synthesis Overexpression of CCNE1 has beenThe protein encoded by RBL1 (RB transcriptional corepressor like 1) is similar in sequence and possibly function to the product of the retinoblastoma 1 (RB1) gene. The RB1 gene product is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and the product of this gene can form a complex