CASC3 Rabbit Polyclonal Antibody, 100ul Recombinant Protein Expression Mutations in REN (renin) have

Mutations in REN (renin) have been shown to cause familial hyperproreninemia

Serine/threonine-protein kinase tousled-like 1 encoded by TLK1 is a serine/threonine kinase that may be involved in the regulation of chromatin assembly

T-cell antigen CD7 is found on thymocytes and mature T cells

although some variants may be subject to nonsense-mediated decay (NMD)

which result in the expression of chimeric proteins that may promote tumor growth

CASC3 Rabbit Polyclonal Antibody, 100ul Recombinant Protein Expression Mutations in REN (renin) haveThe product of this gene is a core component of the exon junction complex (EJC), a protein complex that is deposited on spliced mRNAs at exon exon junctions and functions in nonsense mediated mRNA decay (NMD). The encoded protein binds RNA and interacts with two other EJC core components. It is predominantly located in the cytoplasm, but shuttles into the nucleus where it localizes to nuclear speckles.