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BCL2L12 Polyclonal Antibody, 20ul Enzymes delta subunit) encodes a subunit

SKU: 53030509893

4.4
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BCL2L12 Polyclonal Antibody, 20ul Enzymes delta subunit) encodes a subunitBCL2L12 (BCL2 like 12) encodes a member of a family of proteins containing a Bcl 2 homology domain 2 (BH2). The encoded protein is an anti apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of BCL2L12 has been detected in a number of different cancers. There is a pseudogene for BCL2L12 on chromosome

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Description

delta subunit) encodes a subunit of mitochondrial ATP synthase

and directly interacts with the tumor suppressor p53 to reduce p53 transcriptional activity by reducing p53 protein level in the absence of DNA damage

100mLx6pcs

the key enzyme in polyamine biosynthesis

Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK

BCL2L12 Polyclonal Antibody, 20ul Enzymes delta subunit) encodes a subunitBCL2L12 (BCL2 like 12) encodes a member of a family of proteins containing a Bcl 2 homology domain 2 (BH2). The encoded protein is an anti apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of BCL2L12 has been detected in a number of different cancers. There is a pseudogene for BCL2L12 on chromosome

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