RND3 Polyclonal Antibody, 100ul Drying & Desiccation Mutations in this gene are

Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency

Other variants exist

Studies of the mouse counterpart of MAPK8 suggested that this kinase play a key role in T cell proliferation

they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus which then remains uncleaved to function as a transmembrane anchor

GO annotations related to this gene include poly(A) RNA binding

RND3 Polyclonal Antibody, 100ul Drying & Desiccation Mutations in this gene areThis gene encodes a protein which is a member of the small GTPase protein superfamily. The encoded protein binds only GTP but has no GTPase activity, and appears to act as a negative regulator of cytoskeletal organization leading to loss of adhesion. Multiple alternatively spliced variants, encoding the same protein, have been identified.