I10R2 Polyclonal Antibody, 50ul Site-directed Mutagenesis The protein is thought to

The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis

this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins

this UBA domain family member is being studies as a putative target for mutation in nasopharyngeal carcinomas

this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation

this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors

I10R2 Polyclonal Antibody, 50ul Site-directed Mutagenesis The protein is thought toThe protein encoded by this gene belongs to the cytokine receptor family. It is an accessory chain essential for the active interleukin 10 receptor complex. Coexpression of this and IL10RA proteins has been shown to be required for IL10 induced signal transduction. This gene and three other interferon receptor genes, IFAR2, IFNAR1, and IFNGR2, form a class II cytokine receptor gene cluster located in a small region on chromosome 21.