TAK1(Phospho-Ser412) Rabbit Polyclonal Antibody, 50ul Culture Plate Inserts DNase/RNase-free for confident results

DNase/RNase-free for confident results

Defects in this gene can result in X-linked creatine deficiency syndrome

and maybe involved in cell growth and development

The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete

PTM:Autophosphorylation of Tyr-304 occurs only at abnormally high CSK concentrations in vitro

TAK1(Phospho-Ser412) Rabbit Polyclonal Antibody, 50ul Culture Plate Inserts DNase/RNase-free for confident resultsThe protein encoded by this gene is a member of the serine threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP) and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL 1 this protein forms a kinase complex including TRAF6 MAP3K7P1 TAB1 and MAP3K7P2 TAB2; this complex is required for the activation of nuclear factor kappa