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VPS16 Rabbit Polyclonal Antibody, 20ul 3D Cell Culture Consumables Alkylating agents are potent carcinogens

SKU: 54121363176

4.5
PLN97.20 PLN121.20

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VPS16 Rabbit Polyclonal Antibody, 20ul 3D Cell Culture Consumables Alkylating agents are potent carcinogensVesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps16 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes lysosomes and like their yeast counterparts

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Description

Alkylating agents are potent carcinogens that can result in cell death

q25) of this gene with transcription factor TFE3 gene results in a ASPSCR1-TFE3 fusion protein in alveolar soft part sarcoma and in renal cell carcinomas

The nucleolar protein (DEAD-box helicase 54) encoded by DDX54 interacts in a hormone-dependent manner with nuclear receptors

Mutations of KDR are implicated in infantile capillary hemangiomas

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VPS16 Rabbit Polyclonal Antibody, 20ul 3D Cell Culture Consumables Alkylating agents are potent carcinogensVesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps16 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes lysosomes and like their yeast counterparts

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