HDAC4 Monoclonal Antibody, 100ul[BT-MCA0671] Contamination Detection & Removal An allele mutation and a

An allele mutation and a low-frequency noncoding single-nucleotide polymorphism (SNP) in this gene cause thrombocytopenia-absent radius (TAR) syndrome

The LRRs and NTF2-like domains are required for export activity

a cytosolic phosphoprotein implicated in tumorigenesis

HORMA domains are involved in chromatin binding and play a role in cell cycle regulation

EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B

HDAC4 Monoclonal Antibody, 100ul[BT-MCA0671] Contamination Detection & Removal An allele mutation and aHistones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase acuc apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA