Rho H Polyclonal Antibody, 100ul Yeast Expression It exists as two isoenzymes

It exists as two isoenzymes

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Angelman and Prader-Willi syndromes are associated with loss of function or deletion of genes in the 15q11-q13 region

differ in the number of N-terminal zinc finger motifs that bind DNA and in nuclear localization signal presence

Mutations in this gene result in cataract congenital nuclear autosomal recessive type 2

Rho H Polyclonal Antibody, 100ul Yeast Expression It exists as two isoenzymesThe protein encoded by RHOH is a member of the Ras superfamily of guanosine triphosphate (GTP) metabolizing enzymes. The encoded protein is expressed in hematopoietic cells, where it functions as a negative regulator of cell growth and survival. RHOH may be hypermutated or misexpressed in leukemias and lymphomas. Chromosomal translocations in non Hodgkin's lymphoma occur between this locus and B cell CLL lymphoma 6 (BCL6) on chromosome 3, leading to