RBM8A Rabbit Polyclonal Antibody, 100ul 3D Cell Culture Consumables the gene is expressed in

the gene is expressed in many tissues and exhibits a intracellular vesicular pattern in Panc-1 cells (pancreatic cancer cells)

Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections

is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense

ABC genes are divided into seven distinct subfamilies (ABC1| MDR/TAP| MRP| ALD| OABP| GCN20| and White)

This protein displays arylsulfatase activity at acidic pH

RBM8A Rabbit Polyclonal Antibody, 100ul 3D Cell Culture Consumables the gene is expressed inThis gene encodes a protein with a conserved RNA binding motif. The protein is found predominantly in the nucleus although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present thus coupling pre and post mRNA splicing