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LOXL4 Rabbit Polyclonal Antibody, 20ul sgRNA Oligos The encoded protein is suggested

SKU: 54614601861

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LOXL4 Rabbit Polyclonal Antibody, 20ul sgRNA Oligos The encoded protein is suggestedThis gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue encoding an extracellular copper dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C terminus end appears to be sufficient for amine oxidase activity suggesting that each family member may retain

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Description

The encoded protein is suggested to play a role in the ER-Golgi protein trafficking

There is also a transcribed pseudogene on chromosome 20

Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein| which is thought to be involved in the process of blocking IFN-alpha response by adenovirus

resides within these 3

It is also expressed in T lymphocytes and may function to inhibit interleukin-2 transcription by disrupting calcineurin-dependent dephosphorylation of NFAT

LOXL4 Rabbit Polyclonal Antibody, 20ul sgRNA Oligos The encoded protein is suggestedThis gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue encoding an extracellular copper dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C terminus end appears to be sufficient for amine oxidase activity suggesting that each family member may retain

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