Neu(Phospho Tyr1112) Polyclonal Antibody, 20ul DNA Synthesis The protein encoded by this

The protein encoded by this gene contains two N-terminal doublecortin domains| which bind microtubules and regulate microtubule polymerization| a C-terminal serine/threonine protein kinase domain| which shows substantial homology to Ca2+/calmodulin-dependent protein kinase| and a serine/proline-rich domain in between the doublecortin and the protein kinase domains| which mediates multiple protein-protein interactions

The encoded protein binds numerous other proteins including group I metabotropic glutamate receptors| inositol 1|4|5-trisphosphate receptors and amyloid precursor proteins and has been implicated in diverse biological functions such as neuronal signaling| T-cell activation and trafficking of amyloid beta peptides

This receptor appears to bind the majority of beta-chemokine family members

with high affinity

Catalytic activity:ATP + H(2)O + Ca(2+)(Cis) = ADP + phosphate + Ca(2+)(Trans)

Neu(Phospho Tyr1112) Polyclonal Antibody, 20ul DNA Synthesis The protein encoded by thisThis gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase mediated activation of downstream signalling pathways, such as those involving mitogen activated