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ET-1 Polyclonal Antibody, 50ul Vacuum Filter nine cadherin domains and two

SKU: 55202822530

4.5
USD162.00 USD210.00

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ET-1 Polyclonal Antibody, 50ul Vacuum Filter nine cadherin domains and twoEDN1 encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants.

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Description

nine cadherin domains and two laminin A G-type repeats in their ectodomain

The encoded preproprotein is proteolytically processed to generate multiple intermediate forms and the mature form of the enzyme

Acts by stabilizing RAD51 at stalled replication forks and protecting RAD51 nucleofilaments from the antirecombinogenic activities of FBXO18/FBH1 and BLM

Interleukin-36 beta encoded by IL36B is a member of the interleukin 1 cytokine family

Mutations in this gene are associated with the X-linked lysosomal storage disease mucopolysaccharidosis type II| also known as Hunter syndrome

ET-1 Polyclonal Antibody, 50ul Vacuum Filter nine cadherin domains and twoEDN1 encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants.

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