POLH Polyclonal Antibody, 100ul Custom RNA Oligos PP1 associates with various regulatory

PP1 associates with various regulatory subunits that dictate its subcellular localization and modulate its substrate specificity

It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction

are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals

Alternative splicing results in multiple transcripts variants

but the full-length nature of some variants has not been determined

POLH Polyclonal Antibody, 100ul Custom RNA Oligos PP1 associates with various regulatoryThis gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA directed polymerases. However, it accurately replicates UV damaged DNA; when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV induced DNA damage. This polymerase is thought to be