SYT7 Polyclonal Antibody, 100ul Low-speed Centrifuges Unlike other proteins of the

Unlike other proteins of the group| which cycle in the early secretory pathway and are predominantly associated with post endoplasmic reticulum membranes| the protein encoded by this gene is a non-cycling resident protein of the ER| where it functions as a cargo receptor for glycoproteins

The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family| a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane

bringing newly synthesized histones H3 and H4 to replicating DNA

Upregulation of CDH23 may also be associated with breast cancer

An important paralog of this gene is ADGRG5

SYT7 Polyclonal Antibody, 100ul Low-speed Centrifuges Unlike other proteins of theThis gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium dependent regulation of membrane trafficking in synaptic transmission. A similar protein in rodents mediates hormone secretion and lysosome exocytosis. In humans, expression of this gene has been associated with prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this