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MIA Polyclonal Antibody, 50ul[BT-AP05403] Low retention tips hydroxysteroid 11-beta dehydrogenase 1(HSD11B1) Homo

SKU: 55663532415

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MIA Polyclonal Antibody, 50ul[BT-AP05403] Low retention tips hydroxysteroid 11-beta dehydrogenase 1(HSD11B1) HomoThe product of CHD4 belongs to the SNF2 RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different

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Description

hydroxysteroid 11-beta dehydrogenase 1(HSD11B1) Homo sapiens The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone

a longer form

suggesting that it plays an essential role in histone mRNA decay after replication

In vitro studies have shown a 10- to 15-fold increase in the kinase activity of Lck bound to CD5

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MIA Polyclonal Antibody, 50ul[BT-AP05403] Low retention tips hydroxysteroid 11-beta dehydrogenase 1(HSD11B1) HomoThe product of CHD4 belongs to the SNF2 RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different

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