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DFFB Polyclonal Antibody, 100ul[BT-AP08457] Culture Media Essential for telomere length control

SKU: 56494628606

4.2
SEK141.00 SEK186.00

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DFFB Polyclonal Antibody, 100ul[BT-AP08457] Culture Media Essential for telomere length controlApoptosis is a cell death process that removes toxic and or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40 kD (DFFB) and 45 kD (DFFA) subunits. DFFA is the substrate for caspase 3 and triggers DNA fragmentation during apoptosis. DFF

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Description

Essential for telomere length control

MIM 611054) for background on liprins

Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins| and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions| including fertilization| muscle development| and neurogenesis

resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network

Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity

DFFB Polyclonal Antibody, 100ul[BT-AP08457] Culture Media Essential for telomere length controlApoptosis is a cell death process that removes toxic and or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40 kD (DFFB) and 45 kD (DFFA) subunits. DFFA is the substrate for caspase 3 and triggers DNA fragmentation during apoptosis. DFF

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