Tuberin/TSC2(Phospho-Ser1254) Rabbit Polyclonal Antibody, 50ul Serum with cadherin domains acting as

with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions

a pseudogene of SRSF11 has been found on chromosome 12

this enzyme may be involved in such varied processes as gluconeogenesis

PIAS1 encodes a member of the protein inhibitor of activated STAT (PIAS) family

The N-terminus is poorly conserved and may impart additional roles in developmental regulation

Tuberin/TSC2(Phospho-Ser1254) Rabbit Polyclonal Antibody, 50ul Serum with cadherin domains acting asMutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.