TEFF2 Polyclonal Antibody, 100ul Adeno-associated Virus Packaging GRB2 and SOS1

GRB2 and SOS1

Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED)

This gene is clustered with another 3 candidate taste receptor genes in chromosome 7 and is genetically linked to loci that influence bitter perception

Alternatively spliced transcript variants have been identified for this gene

It binds beta-catenin and negatively regulates Wnt signaling pathway

TEFF2 Polyclonal Antibody, 100ul Adeno-associated Virus Packaging GRB2 and SOS1This gene encodes a member of the tomoregulin family of transmembrane proteins. This protein has been shown to function as both an oncogene and a tumor suppressor depending on the cellular context and may regulate prostate cancer cell invasion. Multiple soluble forms of this protein have been identified that arise from both an alternative splice variant and ectodomain shedding. Additionally, this gene has been found to be hypermethylated in multiple