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DBC-1 Polyclonal Antibody, 50ul Cell Separation and Collection Inactivating variants of this gene

SKU: 57964521074

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SEK162.00 SEK209.00

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DBC-1 Polyclonal Antibody, 50ul Cell Separation and Collection Inactivating variants of this geneCore component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation with the regulation of alternative splicing: the DBIRD complex affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T) rich DNA regions. Inhibits SIRT1 deacetylase activity leading to increasing levels of p53 TP53

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Description

Inactivating variants of this gene result in the recessive Lutheran null phenotype

Cholesterol side-chain cleavage enzyme mitochondrial localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone

GCKR encodes glucokinase regulator belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins

Potassium-transporting ATPase alpha chain 2 encoded by ATP12A belongs to the family of P-type cation transport ATPases

LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue

DBC-1 Polyclonal Antibody, 50ul Cell Separation and Collection Inactivating variants of this geneCore component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation with the regulation of alternative splicing: the DBIRD complex affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T) rich DNA regions. Inhibits SIRT1 deacetylase activity leading to increasing levels of p53 TP53

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