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MDMX Polyclonal Antibody, 50ul Cell Dissociation Good transparency

SKU: 58101054896

4.4
DKK185.00 DKK233.00

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Live Spec

MDMX Polyclonal Antibody, 50ul Cell Dissociation Good transparencyMDM4 encodes a nuclear protein that contains a p53 binding domain at the N terminus and a RING finger domain at the C terminus, and shows structural similarity to p53 binding protein MDM2. Both proteins bind the p53 tumor suppressor protein and inhibit its activity, and have been shown to be overexpressed in a variety of human cancers. However, unlike MDM2 which degrades p53, this protein inhibits p53 by binding its transcriptional activation domain.

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Description

Good transparency

It associates with Ret to transduce Ret-mediated processes such as axonal projection

most of which are necessary for proper CEP55 function

This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA

Riboflavin kinase (RFK

MDMX Polyclonal Antibody, 50ul Cell Dissociation Good transparencyMDM4 encodes a nuclear protein that contains a p53 binding domain at the N terminus and a RING finger domain at the C terminus, and shows structural similarity to p53 binding protein MDM2. Both proteins bind the p53 tumor suppressor protein and inhibit its activity, and have been shown to be overexpressed in a variety of human cancers. However, unlike MDM2 which degrades p53, this protein inhibits p53 by binding its transcriptional activation domain.

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