O-FucT-1 Polyclonal Antibody, 100ul Cytokines and confers oncogenic transformation of

and confers oncogenic transformation of primary cells

The protein plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK)

multiple polyadenylation sites are found in the 3' UTR

Alternative transcriptional splice variants have been found for this gene

The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria

O-FucT-1 Polyclonal Antibody, 100ul Cytokines and confers oncogenic transformation ofPOFUT1 encodes a member of the glycosyltransferase O Fuc family. This enzyme adds O fucose through an O glycosidic linkage to conserved serine or threonine residues in the epidermal growth factor like repeats of a number of cell surface and secreted proteins. O fucose glycans are involved in ligand induced receptor signaling. Alternative splicing of this gene results in two transcript variants encoding different isoforms.