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p53(Phospho Ser15) Polyclonal Antibody, 100ul 3D Culture including 12 transmembrane (TM) domains

SKU: 5838350374

4.4
EUR141.00 EUR181.00

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p53(Phospho Ser15) Polyclonal Antibody, 100ul 3D Culture including 12 transmembrane (TM) domainsThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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Description

including 12 transmembrane (TM) domains

TBX2 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain

TP73 encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development

This gene may play a role in the progression of several malignancies including melanoma

cerebellar Purkinje cells

p53(Phospho Ser15) Polyclonal Antibody, 100ul 3D Culture including 12 transmembrane (TM) domainsThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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