Integrin AlphaL Polyclonal Antibody, 50ul Primary Antibodies This gene is upregulated in

This gene is upregulated in many known tumors and its expression is correlated with tumor stage and progression

Several alpha defensin genes are clustered on chromosome 8

Contains 2 RanBD1 domains

It is thought to play a role in the tumorigenesis of colorectal cancers and the proliferative control of normal cells

secreted proteins lacking transmembrane and intracellular domains may function as extracellular antagonists to cytokine signaling

Integrin AlphaL Polyclonal Antibody, 50ul Primary Antibodies This gene is upregulated inITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function associated antigen 1 (LFA 1), which is expressed on all leukocytes. LFA 1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1 3