DBLOH Polyclonal Antibody, 50ul Filtration The peptide binding cleft accommodates

The peptide binding cleft accommodates peptides of 10-30 residues

Alternative translation initiation site usage results in the production of different isoforms (PMID:12105216)

This gene contains at least 14 exons| and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons

13) family

and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase

DBLOH Polyclonal Antibody, 50ul Filtration The peptide binding cleft accommodatesThis gene encodes an inhibitor of apoptosis protein (IAP) binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young adult onset of nonsyndromic deafness 64. Alternative splicing results in multiple transcript