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ASPP2 Polyclonal Antibody, 100ul Funnels This gene encodes multiple isoforms

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ASPP2 Polyclonal Antibody, 100ul Funnels This gene encodes multiple isoformsThis gene encodes a member of the ASPP (apoptosis stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein protein interactions. It is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family. Multiple transcript variants encoding different

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Description

This gene encodes multiple isoforms that may undergo similar proteolytic processing

The protein encoded by this gene is cell-cycle regulated| and has nuclear localization

The protein encoded by SLC6A11 (solute carrier family 6 member 11) is a sodium-dependent transporter that uptakes gamma-aminobutyric acid (GABA)

which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB

and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events

ASPP2 Polyclonal Antibody, 100ul Funnels This gene encodes multiple isoformsThis gene encodes a member of the ASPP (apoptosis stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein protein interactions. It is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family. Multiple transcript variants encoding different

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