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CLP1 Polyclonal Antibody, 50ul Mammalian Expression Mice deficient in these cytokines

SKU: 60070052940

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SEK162.00 SEK194.00

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CLP1 Polyclonal Antibody, 50ul Mammalian Expression Mice deficient in these cytokinesThis gene encodes a member of the Clp1 family. The encoded protein is a multifunctional kinase which is a component of the tRNA splicing endonuclease complex and a component of the pre mRNA cleavage complex II. This protein is implicated in tRNA, mRNA, and siRNA maturation. Mutations in this gene are associated with pontocerebellar hypoplasia type 10 (PCH10). Alternatively splice transcript variants encoding different isoforms have been found for this

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Description

Mice deficient in these cytokines

This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins

Serine/threonine-protein kinase MARK2 is an important regulator of cell polarity in epithelial and neuronal cells

Mutations in the TFR2 gene result in hereditary hemochromatosis type III (HFE3)

The protein contains both SH2 and SH3 domains which are often found in intracellular kinases

CLP1 Polyclonal Antibody, 50ul Mammalian Expression Mice deficient in these cytokinesThis gene encodes a member of the Clp1 family. The encoded protein is a multifunctional kinase which is a component of the tRNA splicing endonuclease complex and a component of the pre mRNA cleavage complex II. This protein is implicated in tRNA, mRNA, and siRNA maturation. Mutations in this gene are associated with pontocerebellar hypoplasia type 10 (PCH10). Alternatively splice transcript variants encoding different isoforms have been found for this

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