MMAC Rabbit Polyclonal Antibody, 20ul Microplate Mixer Mutations in REN (renin) have

Mutations in REN (renin) have been shown to cause familial hyperproreninemia

This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases

ZNF280D (Zinc Finger Protein 280D) is a Protein Coding gene

unlike NT1 receptor

This kinase has been reported to play roles in many different cellular processes| such as cell adhesion| cell transformation| cell cycle checkpoint| and cell volume control

MMAC Rabbit Polyclonal Antibody, 20ul Microplate Mixer Mutations in REN (renin) haveThe exact function of the protein encoded by this gene is not known however its C terminal region shows similarity to TonB a bacterial protein involved in energy transduction for cobalamin (vitamin B12) uptake. Hence it is postulated that this protein may have a role in the binding and intracellular trafficking of cobalamin. Mutations in this gene are associated with methylmalonic aciduria and homocystinuria type cblC.