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REV1 Polyclonal Antibody, 20ul Vessels |tissue specificity:Expressed in umbilical vein

SKU: 60250683176

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REV1 Polyclonal Antibody, 20ul Vessels |tissue specificity:Expressed in umbilical veinThis gene encodes a protein with similarity to the S. cerevisiae mutagenesis protein Rev1. The Rev1 proteins contain a BRCT domain, which is important in protein protein interactions. A suggested role for the human Rev1 like protein is as a scaffold that recruits DNA polymerases involved in translesion synthesis (TLS) of damaged DNA.

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Description

|tissue specificity:Expressed in umbilical vein endothelial cells and several cancer cell lines (at protein level)

CST2 is located in the cystatin locus and encodes a secreted thiol protease inhibitor found at high levels in saliva

leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3

and has RNA chaperone activity that may be involved in template switch

BCL2 encodes an integral outer mitochondrial membrane protein (BCL2

REV1 Polyclonal Antibody, 20ul Vessels |tissue specificity:Expressed in umbilical veinThis gene encodes a protein with similarity to the S. cerevisiae mutagenesis protein Rev1. The Rev1 proteins contain a BRCT domain, which is important in protein protein interactions. A suggested role for the human Rev1 like protein is as a scaffold that recruits DNA polymerases involved in translesion synthesis (TLS) of damaged DNA.

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