WTAP Polyclonal Antibody, 20ul PCR Series The protein encoded by this

The protein encoded by this gene is included in class I of the sirtuin family

first described as a putative integral membrane pentraxin that interacts with neuronal pentraxin 1 and 2

it suppresses the activation of MAP kinase by oncogenic ras in extracts of Xenopus oocytes

Gene Ontology (GO) annotations related to this gene include calcium ion binding

it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins

WTAP Polyclonal Antibody, 20ul PCR Series The protein encoded by thisThe Wilms tumor suppressor gene WT1 appears to play a role in both transcriptional and posttranscriptional regulation of certain cellular genes. WTAP encodes a WT1 associating protein, which is a ubiquitously expressed nuclear protein. Like WT1 protein, pre mRNA splicing regulator WTAP is localized throughout the nucleoplasm as well as in speckles and partially colocalizes with splicing factors. Alternative splicing of this gene results in several