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KLHL3 is ubiquitously expressed and encodes kelch like family member 3 which has an N-terminal BTB domain followed by a BACK domain and six kelch-like repeats in the C-terminus

The encoded protein also contains fibronectin type III repeats and an epidermal growth factor repeat

The protein lacks the cytoplasmic domain characteristic of other cadherins

This protein may form oligomeric complexes with family members

CD58 Polyclonal Antibody, 50ul[BT-AP02350] Bottles Take your research to newCyclin D1 encoded by CCND1 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6,